diff --git a/CHANGELOG.md b/CHANGELOG.md
index 9b1f9310aa..1d2cdf84c2 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -2,6 +2,9 @@
 
 ## v21.07: (Upcoming Release)
 
+### bdev
+Change `spdk_bdev_read_blocks_with_md` arg offset definiton from int64_t to uint64_t.
+
 ### dpdk
 
 Updated DPDK submodule to DPDK 21.02.
diff --git a/include/spdk/bdev.h b/include/spdk/bdev.h
index 19b265735f..36cdb02a30 100644
--- a/include/spdk/bdev.h
+++ b/include/spdk/bdev.h
@@ -803,7 +803,7 @@ int spdk_bdev_read_blocks(struct spdk_bdev_desc *desc, struct spdk_io_channel *c
  *   * -ENOMEM - spdk_bdev_io buffer cannot be allocated
  */
 int spdk_bdev_read_blocks_with_md(struct spdk_bdev_desc *desc, struct spdk_io_channel *ch,
-				  void *buf, void *md, int64_t offset_blocks, uint64_t num_blocks,
+				  void *buf, void *md, uint64_t offset_blocks, uint64_t num_blocks,
 				  spdk_bdev_io_completion_cb cb, void *cb_arg);
 
 /**
diff --git a/lib/bdev/bdev.c b/lib/bdev/bdev.c
index 42d82c6817..3c82cef970 100644
--- a/lib/bdev/bdev.c
+++ b/lib/bdev/bdev.c
@@ -3658,7 +3658,7 @@ _bdev_io_check_md_buf(const struct iovec *iovs, const void *md_buf)
 
 static int
 bdev_read_blocks_with_md(struct spdk_bdev_desc *desc, struct spdk_io_channel *ch, void *buf,
-			 void *md_buf, int64_t offset_blocks, uint64_t num_blocks,
+			 void *md_buf, uint64_t offset_blocks, uint64_t num_blocks,
 			 spdk_bdev_io_completion_cb cb, void *cb_arg)
 {
 	struct spdk_bdev *bdev = spdk_bdev_desc_get_bdev(desc);
@@ -3715,7 +3715,7 @@ spdk_bdev_read_blocks(struct spdk_bdev_desc *desc, struct spdk_io_channel *ch,
 
 int
 spdk_bdev_read_blocks_with_md(struct spdk_bdev_desc *desc, struct spdk_io_channel *ch,
-			      void *buf, void *md_buf, int64_t offset_blocks, uint64_t num_blocks,
+			      void *buf, void *md_buf, uint64_t offset_blocks, uint64_t num_blocks,
 			      spdk_bdev_io_completion_cb cb, void *cb_arg)
 {
 	struct iovec iov = {